![Beyond Loss of Frataxin: the Complex Molecular Pathology of Friedreich Ataxia - Marguerite V Evans-Galea - Discovery Medicine Beyond Loss of Frataxin: the Complex Molecular Pathology of Friedreich Ataxia - Marguerite V Evans-Galea - Discovery Medicine](https://www.discoverymedicine.com/Marguerite-V-Evans-Galea/files/2014/01/discovery_medicine_no_91_marguerite_v_evans_galea_figure_1.jpg)
Beyond Loss of Frataxin: the Complex Molecular Pathology of Friedreich Ataxia - Marguerite V Evans-Galea - Discovery Medicine
![FXN gene methylation may help diagnose carrier status in FA | Small chemical tags in DNA found to ID carriers with no symptoms | Friedreich's Ataxia News FXN gene methylation may help diagnose carrier status in FA | Small chemical tags in DNA found to ID carriers with no symptoms | Friedreich's Ataxia News](https://friedreichsataxianews.com/wp-content/uploads/2022/11/DNA-Strand.png)
FXN gene methylation may help diagnose carrier status in FA | Small chemical tags in DNA found to ID carriers with no symptoms | Friedreich's Ataxia News
![Schematic diagram of the FXN and GFP genes containing intronic GAA·TTC... | Download Scientific Diagram Schematic diagram of the FXN and GFP genes containing intronic GAA·TTC... | Download Scientific Diagram](https://www.researchgate.net/publication/23285945/figure/fig8/AS:324926885122065@1454480014597/Schematic-diagram-of-the-FXN-and-GFP-genes-containing-intronic-GAATTC-repeats-A.png)
Schematic diagram of the FXN and GFP genes containing intronic GAA·TTC... | Download Scientific Diagram
Structure–Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe–S Assembly Complex | Biochemistry
![Gene regulation and epigenetics in Friedreich's ataxia - Yandim - 2013 - Journal of Neurochemistry - Wiley Online Library Gene regulation and epigenetics in Friedreich's ataxia - Yandim - 2013 - Journal of Neurochemistry - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/40192b0c-d0cf-40fa-bb4c-f4725cfe24ba/jnc12254-fig-0001-m.jpg)
Gene regulation and epigenetics in Friedreich's ataxia - Yandim - 2013 - Journal of Neurochemistry - Wiley Online Library
![The 5' end of the frataxin (FXN) gene showing the minimal promoter,... | Download Scientific Diagram The 5' end of the frataxin (FXN) gene showing the minimal promoter,... | Download Scientific Diagram](https://www.researchgate.net/publication/221892301/figure/fig1/AS:202573735829511@1425308750544/The-5-end-of-the-frataxin-FXN-gene-showing-the-minimal-promoter-exon-1-and-the.png)
The 5' end of the frataxin (FXN) gene showing the minimal promoter,... | Download Scientific Diagram
![CRISPR-Cas9 Gene Editing of Hematopoietic Stem Cells from Patients with Friedreich's Ataxia: Molecular Therapy - Methods & Clinical Development CRISPR-Cas9 Gene Editing of Hematopoietic Stem Cells from Patients with Friedreich's Ataxia: Molecular Therapy - Methods & Clinical Development](https://www.cell.com/cms/attachment/e950a66e-b6fb-4e19-b9e7-1ea7429a70ec/fx1_lrg.jpg)
CRISPR-Cas9 Gene Editing of Hematopoietic Stem Cells from Patients with Friedreich's Ataxia: Molecular Therapy - Methods & Clinical Development
![Needles&Neurons on Twitter: "In the FXN gene, a GAA sequence repeats between 7-22 times. In Friedreich ataxia, this GAA triplet of DNA code is expanded, sometime repeated hundreds of times due to Needles&Neurons on Twitter: "In the FXN gene, a GAA sequence repeats between 7-22 times. In Friedreich ataxia, this GAA triplet of DNA code is expanded, sometime repeated hundreds of times due to](https://pbs.twimg.com/media/E_pegcZXIAURfho.jpg)
Needles&Neurons on Twitter: "In the FXN gene, a GAA sequence repeats between 7-22 times. In Friedreich ataxia, this GAA triplet of DNA code is expanded, sometime repeated hundreds of times due to
![Molecular Mechanisms and Therapeutics for the GAA·TTC Expansion Disease Friedreich Ataxia | SpringerLink Molecular Mechanisms and Therapeutics for the GAA·TTC Expansion Disease Friedreich Ataxia | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs13311-019-00764-x/MediaObjects/13311_2019_764_Fig1_HTML.png)
Molecular Mechanisms and Therapeutics for the GAA·TTC Expansion Disease Friedreich Ataxia | SpringerLink
![IJMS | Free Full-Text | The NRF2 Signaling Network Defines Clinical Biomarkers and Therapeutic Opportunity in Friedreich's Ataxia IJMS | Free Full-Text | The NRF2 Signaling Network Defines Clinical Biomarkers and Therapeutic Opportunity in Friedreich's Ataxia](https://www.mdpi.com/ijms/ijms-21-00916/article_deploy/html/images/ijms-21-00916-g001.png)
IJMS | Free Full-Text | The NRF2 Signaling Network Defines Clinical Biomarkers and Therapeutic Opportunity in Friedreich's Ataxia
![Advantages and Limitations of Gene Therapy and Gene Editing for Friedreich's Ataxia | Semantic Scholar Advantages and Limitations of Gene Therapy and Gene Editing for Friedreich's Ataxia | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/f366cff4347b00956e4b89b209e629aca81ade75/4-Figure1-1.png)
Advantages and Limitations of Gene Therapy and Gene Editing for Friedreich's Ataxia | Semantic Scholar
![High Levels of Frataxin Overexpression Lead to Mitochondrial and Cardiac Toxicity in Mouse Models: Molecular Therapy - Methods & Clinical Development High Levels of Frataxin Overexpression Lead to Mitochondrial and Cardiac Toxicity in Mouse Models: Molecular Therapy - Methods & Clinical Development](https://www.cell.com/cms/asset/ad5e32bf-6122-471c-921e-94e6e9b686c8/fx1.jpg)
High Levels of Frataxin Overexpression Lead to Mitochondrial and Cardiac Toxicity in Mouse Models: Molecular Therapy - Methods & Clinical Development
![PDF] Friedreich ataxia : investigating the relationships between mismatch repair gene expression, FXN gene expression and GAA repeat instability in human and mouse cells and tissues | Semantic Scholar PDF] Friedreich ataxia : investigating the relationships between mismatch repair gene expression, FXN gene expression and GAA repeat instability in human and mouse cells and tissues | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/be2f14fa6917ce3ce4ed32cabf4433380a59e947/33-Figure1.7-1.png)